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KMID : 0388419960060010009
Konkuk Journal of Medical Sciences
1996 Volume.6 No. 1 p.9 ~ p.24
A Study on the Effect of Obesity and Age for Hypertension by Disease model and Conetic Polymorphism



Abstract
We studied the prevalance of hypertension and the effect of sex, age, body mass index(BMI) and Broca index(BRI(%)) by Disease Model for hypertension. We selected the 2,973 persons who had been taken anual routine health examination from hospital
of
college of medicine, Kon-Kuk University.
Obesity is a cause of reversible hypertension that is typically associated with increases in both peripheral resistance and cardiac output. There were significant differences in the levels of blood pressure among body mass index, Broca index, age
and
sex by Disease Model for hypertension. The effects of variance component of BMI, age, sex and error for systolic blood pressure and diastolic blood pressure were 13.1% and 13.5%, 8.8% and 7.0%, 2.8% and 4.1% and 75.3% and 75.4%, respectively.
The Disease Models and the tools of molecular biology provide the means to define the environmental factors and the genetic basis of hypertensive disease.
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